This formulation uses the power of nature to unlock the full potential for optimum function. PAIN Formula focuses on several key receptors, using proven plant-based materials, to aid in a safe and effective means of supporting and recalibrating stimulated pain receptors.
Quantity: 90 capsules
CBD: 750 mg in bottle
Directions: Take 1-3 capsules every 8 hours for pain. Do not exceed 9 capsules in 24 hours. Take with food and 8 fluid ounces of water.
Cannabidiol (CBD): Cannabidiol has demonstrated preliminary efficacy for a range of physical and mental health care problems. Reviewed studies suggested that cannabinoids could improve sleep quality, decrease sleep disturbances, and decrease sleep onset latency.
Curcumin: Curcuma longa has shown potent anti-inflammatory effects, scavenges both nitrous oxide and superoxide, inhibits COX -2 Cyclooxygenase, and upregulates peroxisome proliferator-activated receptor-y (PPAR-y). This leads to the suppression of proinflammatory cytokine, TNF-a expression and release.
Boswellia: Boswellia serrara contains boswellic acids, which were found to selectively inhibit the synthesis of the pro-inflammatory enzyme 5-lipoxygenase (5-LO), as well as 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB-4), which cause bronchoconstriction, chemotaxis, and increased vascular permeability. These acids have also been show to trigger inhibition of human leukocyte elastase (HLE).
Devil’s Claw: Has been found to suppress oxidative/nitrosative stress and inflammatory responses including nitric oxide and reactive oxygen species production, phosphorylation of cytosolic phospholipases A2, and upregulation of antioxidative stress pathways in spinal cord injuries.
Bromelain: Ananas comosus has been shown to mitigate neuropathic pain by enhancing NfF-1 and NrF2 activities and subsequently increasing antioxidant effects. It has also been found to decrease post-surgical pain and swelling.
Ginger Extract: Contains 6-shogaol which has be show to reduce pain symptoms in painful diabetic neuropathy via its effect on decreasing TRPV1 and NMDAR2B expressions in the spinal cord.
Green Tea Extract: EGCG has been shown to significantly suppress interleukin-1 beta (IL-1B)-induced elevation of mRNA expression of pain mediators, proinflammatory cytokines, and matrix metalloproteinases (MMPs) in vitro.
Resveratrol: This natural phenol has been found to have antinociceptive effects on visceral hyperalgesia through inhibition of spinal TRAF6/NF-kB mediated neuroinflammation.
Capsaicin: Induces desensitization of TRPV1 receptors and the depletion of pain signaling neuropeptides in nerve fibers, including Substance P, leading to analgesic effects.
Green Maeng Da: Myitragyna speciosa dampens nociceptive responses through occupation of the MGM-9 kappa-opioid receptor and demonstrated anti-inflammatory effects as alpha-2 agonists.
Corydalis Root: Exhibits neural mediated analgesic effects through pH mediated inhibition of acid-sensing ion channels in dorsal root ganglion cells.
Cat’s Claw: Known as the “life-giving vine of Peru”, is a thick woody vine indigenous to the Amazon rainforest. The mechanism of Cat’s Claw appears to be as an inhibitor of TNFα and an antioxidant. Some research shows that Cat’s Claw may help with those experiencing osteoarthritis and pain caused by inflammation.
Marshmallow Root: Because marshmallow root is mucilaginous (slimy), when taken internally it is classified as a demulcent, it’s an herb that forms a soothing film over the mucous membrane. Marshmallow root has one of the strongest antioxidant effects of many herbs that have been tested. Marshmallow root has been shown to be effective in reducing skin inflammation. Research shows it to be helpful in treating Crohn’s disease, ulcerative colitis and other inflammatory bowel diseases. It’s also soothing to stomach ulcers and potential treats simple indigestion.
Humulene: A terpene abundant in the hops plant, has been shown to help control inflammation and boost the body’s immune responses.
Caryophyllene: A terpene with a peppery flavor, is the only terpene known to act on the endocannabinoid system. By activating CB2 receptors it plays a key role in the reduction of pain sensation and inflammation
We do not ship this product the following states, cities and counties in the US where there are potential legal issues with Maeng Da: Alabama, Arkansas, Indiana, Rhode Island, Tennessee, Vermont, Wisconsin. Sarasota County, Union County, Denver CA, San Diego CA, Jerseyville IL, City of Oceanside CA, Ontario OR, Alton IL, and Columbus MS. Furthermore, Maeng Da is also banned in the following countries where shipment cannot be executed: Australia, Burma, Denmark, Finland, Israel, Lithuania, Malaysia, Myanmar, Poland, Romania, South Korea, Sweden, Thailand, United Kingdom, Vietnam.
FOR ADULT USE ONLY. Keep out of reach of children. When using dietary supplements please consult your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating. Discontinue if you experience an adverse effect. Store bottles tightly closed in a cool dry place, away from light. Do not use if safety seal is broken or missing.
ANXIETY: Avoid alcohol and sedatives while taking this product.
PAIN: Do not use if you are taking blood thinning medication or have anemia. Do not use if you are allergic pineapple, latex, wheat, celery, papain, carrot, fennel, cypress, or pollen.
FOCUS: Do not use if you are taking blood thinning medication or have anemia.
VIRAL: Do not use if you are taking blood thinning medication or have anemia.
SLEEP: Do not drive or operate heavy machinery after taking. Avoid alcohol and sedatives while taking this product. Do not use if you are taking blood thinning medication or have anemia. Do not use if you are allergic to rag weed or latex.
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